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Covid-19 NIH Archive
Overview
Since the onset of the COVID-19 pandemic, information on testing, prevention, and the clinical spectrum of SARS-CoV-2 infection has evolved quickly.
Overview of COVID-19
COVID-19 epidemiology, disparities in care, and SARS-CoV-2 variants.
SARS-CoV-2 Testing
Who should be tested and what tests are recommended.
Prevention of SARS-CoV-2
Prevention measures and vaccines to mitigate the spread of COVID-19.
Clinical Spectrum
Clinical manifestations of acute SARS-CoV-2 infection and potential long-term sequelae.
Prioritization of Therapeutics
Guidance for prioritizing anti-SARS-CoV-2 therapeutics amid logistical constraints.
Management
The Panel provides guidance on the clinical management of COVID-19, including care for critically ill patients.
Clinical Management of Adults
These sections contain recommendations for managing adults with COVID-19 who have a range of clinical presentations.
Critical Care for Adults
These sections provide guidance for clinicians caring for critically ill adults with COVID-19.
Clinical Management of Children
These sections contain recommendations for managing children with COVID-19 or multisystem inflammatory syndrome in children (MIS-C).
Critical Care for Children
These sections provide guidance for clinicians caring for critically ill children with COVID-19.
Therapies
The Panel reviews the most recent clinical data to develop treatment recommendations for clinicians who are caring for patients with COVID-19.
Antivirals, Including Antibody Products
These sections summarize data on the use of antiviral agents for the treatment of COVID-19.
Summary Recommendations
Remdesivir
Remdesivir: Selected Clinical Trial Data
Ritonavir-Boosted Nirmatrelvir (Paxlovid)
Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications
Molnupiravir
Anti-SARS-CoV-2 Monoclonal Antibodies
Anti-SARS-CoV-2 Monoclonal Antibodies: Selected Clinical Trial Data
COVID-19 Convalescent Plasma
COVID-19 Convalescent Plasma: Selected Clinical Trial Data
Interferons
Interferons: Selected Clinical Trial Data
Table: Characteristics of Antiviral Agents, Including Antibody Products
Immunomodulators
These sections summarize data on corticosteroids, IL-6 inhibitors, JAK inhibitors, and other immunomodulators.
Systemic Corticosteroids
Systemic Corticosteroids: Selected Clinical Trial Data
Inhaled Corticosteroids
Inhaled Corticosteroids: Selected Clinical Trial Data
Interleukin-6 Inhibitors
Interleukin-6 Inhibitors: Selected Clinical Trial Data
Janus Kinase Inhibitors
Janus Kinase Inhibitors: Selected Clinical Trial Data
Abatacept
Infliximab
Interleukin-1 Inhibitors
Vilobelimab
Table: Characteristics of Immunomodulators
Miscellaneous Drugs
These sections summarize data on metformin, fluvoxamine, and other miscellaneous drugs.
Antithrombotic Therapy
This section discusses thromboembolism screening, prevention, and treatment in people with COVID-19.
Supplements
These sections provide information on the evaluation of supplements in COVID-19 care.
Concomitant Medications
This section offers guidance on the use of concomitant medications in people with COVID-19.
Special Populations
The COVID-19 Treatment Guidelines discuss what clinicians need to consider when managing COVID-19 in pregnant people, people with HIV, and other special patient populations.
Immunocompromised
Special considerations when managing COVID-19 in people who are immunocompromised.
Cancer
Special considerations when managing people with COVID-19 and cancer.
Transplant
Special considerations when managing COVID-19 in transplant candidates, recipients, and donors.
Pregnancy
Management of COVID-19 during pregnancy and lactation.
Influenza
Guidance on vaccinations, testing, and treatments when influenza and SARS-CoV-2 are cocirculating.
HIV
View considerations related to preventing and treating SARS-CoV-2 infection in people with HIV.